The family of 39-year-old Strabane man Sean Thomas Diver are growing concerned for his wellbeing after he was reported missing on Wednesday night, January 27.
Mr Diver was last seen in the Townsend Street area last night.
He is described as being abut 5ft 7ins tall, of a slim build and with brown hair. He has tattoos on his neck.
Police and other emergency services have been carrying out searches in the town.
Anyone who has seen Mr Diver since about 10pm last night is asked to contact police on 101.